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α human clec5a antibody  (R&D Systems)


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    R&D Systems α human clec5a antibody
    Immunofluorescent analysis of <t>CLEC5A</t> in lungs of mice exposed to (A) FA or (B) CS for 6 months. Arrows indicate alveolar macrophage (representative of 4 mice). CLEC5A surface expression was measured on (C) peripheral blood monocytes and (D and E) alveolar macrophage (F4/80hiCD11blo) from FA- and CS- exposed mice. Dashed line represents isotype control, solid line represents CLEC5A (n=5 mice). (F) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage. (G) CLEC5A expression on lung macrophage of never smokers (NS) and current smoker (S) (n=4 subjects/group). (H) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage.
    α Human Clec5a Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α human clec5a antibody/product/R&D Systems
    Average 92 stars, based on 1 article reviews
    α human clec5a antibody - by Bioz Stars, 2026-06
    92/100 stars

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    1) Product Images from "CLEC5A Mediates Macrophage Function and COPD Pathologies 1 "

    Article Title: CLEC5A Mediates Macrophage Function and COPD Pathologies 1

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    doi: 10.4049/jimmunol.1500978

    Immunofluorescent analysis of CLEC5A in lungs of mice exposed to (A) FA or (B) CS for 6 months. Arrows indicate alveolar macrophage (representative of 4 mice). CLEC5A surface expression was measured on (C) peripheral blood monocytes and (D and E) alveolar macrophage (F4/80hiCD11blo) from FA- and CS- exposed mice. Dashed line represents isotype control, solid line represents CLEC5A (n=5 mice). (F) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage. (G) CLEC5A expression on lung macrophage of never smokers (NS) and current smoker (S) (n=4 subjects/group). (H) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage.
    Figure Legend Snippet: Immunofluorescent analysis of CLEC5A in lungs of mice exposed to (A) FA or (B) CS for 6 months. Arrows indicate alveolar macrophage (representative of 4 mice). CLEC5A surface expression was measured on (C) peripheral blood monocytes and (D and E) alveolar macrophage (F4/80hiCD11blo) from FA- and CS- exposed mice. Dashed line represents isotype control, solid line represents CLEC5A (n=5 mice). (F) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage. (G) CLEC5A expression on lung macrophage of never smokers (NS) and current smoker (S) (n=4 subjects/group). (H) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage.

    Techniques Used: Expressing, Fluorescence

    BAL macrophage (5×104) were stimulated with (A) control IgG, α-CLEC5A activating antibody (10 ug/ml), LPS (10 ng/ml), or both for 24hrs. Similarly, BAL macrophage (5×104) were stimulated with (B) control IgG, α-CLEC5A activating antibody (10 ug/ml), GM-CSF (20 ng/ml), or both for 24hrs. TNFα was measured by ELISA. Data are mean +/− sem of 3 experiments performed in duplicate. * p<0.05 compared to FA mice.
    Figure Legend Snippet: BAL macrophage (5×104) were stimulated with (A) control IgG, α-CLEC5A activating antibody (10 ug/ml), LPS (10 ng/ml), or both for 24hrs. Similarly, BAL macrophage (5×104) were stimulated with (B) control IgG, α-CLEC5A activating antibody (10 ug/ml), GM-CSF (20 ng/ml), or both for 24hrs. TNFα was measured by ELISA. Data are mean +/− sem of 3 experiments performed in duplicate. * p<0.05 compared to FA mice.

    Techniques Used: Enzyme-linked Immunosorbent Assay

    (A and B) WT and Clec5a−/− mice were exposed to CS for up to 6 months to evaluate lung remodeling as assessed by MLI (Data are mean +/− SEM, n=7–8). (C) Pulmonary inflammation was assessed by enumerating the total cells in BAL. (D) Cytokine levels in BAL of WT and Clec5a−/− mice (n=5–8). (E) mRNA expression levels in BAL macrophage of WT and Clec5a−/− mice (n=5–6). * p<0.05 compared to FA mice. # p<0.05 compared to wild-type mice.
    Figure Legend Snippet: (A and B) WT and Clec5a−/− mice were exposed to CS for up to 6 months to evaluate lung remodeling as assessed by MLI (Data are mean +/− SEM, n=7–8). (C) Pulmonary inflammation was assessed by enumerating the total cells in BAL. (D) Cytokine levels in BAL of WT and Clec5a−/− mice (n=5–8). (E) mRNA expression levels in BAL macrophage of WT and Clec5a−/− mice (n=5–6). * p<0.05 compared to FA mice. # p<0.05 compared to wild-type mice.

    Techniques Used: Expressing



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    α human clec5a antibody  (R&D Systems)
    92
    R&D Systems α human clec5a antibody
    Immunofluorescent analysis of <t>CLEC5A</t> in lungs of mice exposed to (A) FA or (B) CS for 6 months. Arrows indicate alveolar macrophage (representative of 4 mice). CLEC5A surface expression was measured on (C) peripheral blood monocytes and (D and E) alveolar macrophage (F4/80hiCD11blo) from FA- and CS- exposed mice. Dashed line represents isotype control, solid line represents CLEC5A (n=5 mice). (F) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage. (G) CLEC5A expression on lung macrophage of never smokers (NS) and current smoker (S) (n=4 subjects/group). (H) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage.
    α Human Clec5a Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α human clec5a antibody/product/R&D Systems
    Average 92 stars, based on 1 article reviews
    α human clec5a antibody - by Bioz Stars, 2026-06
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    Immunofluorescent analysis of CLEC5A in lungs of mice exposed to (A) FA or (B) CS for 6 months. Arrows indicate alveolar macrophage (representative of 4 mice). CLEC5A surface expression was measured on (C) peripheral blood monocytes and (D and E) alveolar macrophage (F4/80hiCD11blo) from FA- and CS- exposed mice. Dashed line represents isotype control, solid line represents CLEC5A (n=5 mice). (F) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage. (G) CLEC5A expression on lung macrophage of never smokers (NS) and current smoker (S) (n=4 subjects/group). (H) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: CLEC5A Mediates Macrophage Function and COPD Pathologies 1

    doi: 10.4049/jimmunol.1500978

    Figure Lengend Snippet: Immunofluorescent analysis of CLEC5A in lungs of mice exposed to (A) FA or (B) CS for 6 months. Arrows indicate alveolar macrophage (representative of 4 mice). CLEC5A surface expression was measured on (C) peripheral blood monocytes and (D and E) alveolar macrophage (F4/80hiCD11blo) from FA- and CS- exposed mice. Dashed line represents isotype control, solid line represents CLEC5A (n=5 mice). (F) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage. (G) CLEC5A expression on lung macrophage of never smokers (NS) and current smoker (S) (n=4 subjects/group). (H) Average number of CLEC5A+ cells and median fluorescence intensity of CLEC5A on alveolar macrophage.

    Article Snippet: CLEC5A was assessed with α-human CLEC5A antibody (clone 283834, R&D Systems) and α-CD45 (eBioscience) using a FACSCalibur and FlowJo software.

    Techniques: Expressing, Fluorescence

    BAL macrophage (5×104) were stimulated with (A) control IgG, α-CLEC5A activating antibody (10 ug/ml), LPS (10 ng/ml), or both for 24hrs. Similarly, BAL macrophage (5×104) were stimulated with (B) control IgG, α-CLEC5A activating antibody (10 ug/ml), GM-CSF (20 ng/ml), or both for 24hrs. TNFα was measured by ELISA. Data are mean +/− sem of 3 experiments performed in duplicate. * p<0.05 compared to FA mice.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: CLEC5A Mediates Macrophage Function and COPD Pathologies 1

    doi: 10.4049/jimmunol.1500978

    Figure Lengend Snippet: BAL macrophage (5×104) were stimulated with (A) control IgG, α-CLEC5A activating antibody (10 ug/ml), LPS (10 ng/ml), or both for 24hrs. Similarly, BAL macrophage (5×104) were stimulated with (B) control IgG, α-CLEC5A activating antibody (10 ug/ml), GM-CSF (20 ng/ml), or both for 24hrs. TNFα was measured by ELISA. Data are mean +/− sem of 3 experiments performed in duplicate. * p<0.05 compared to FA mice.

    Article Snippet: CLEC5A was assessed with α-human CLEC5A antibody (clone 283834, R&D Systems) and α-CD45 (eBioscience) using a FACSCalibur and FlowJo software.

    Techniques: Enzyme-linked Immunosorbent Assay

    (A and B) WT and Clec5a−/− mice were exposed to CS for up to 6 months to evaluate lung remodeling as assessed by MLI (Data are mean +/− SEM, n=7–8). (C) Pulmonary inflammation was assessed by enumerating the total cells in BAL. (D) Cytokine levels in BAL of WT and Clec5a−/− mice (n=5–8). (E) mRNA expression levels in BAL macrophage of WT and Clec5a−/− mice (n=5–6). * p<0.05 compared to FA mice. # p<0.05 compared to wild-type mice.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: CLEC5A Mediates Macrophage Function and COPD Pathologies 1

    doi: 10.4049/jimmunol.1500978

    Figure Lengend Snippet: (A and B) WT and Clec5a−/− mice were exposed to CS for up to 6 months to evaluate lung remodeling as assessed by MLI (Data are mean +/− SEM, n=7–8). (C) Pulmonary inflammation was assessed by enumerating the total cells in BAL. (D) Cytokine levels in BAL of WT and Clec5a−/− mice (n=5–8). (E) mRNA expression levels in BAL macrophage of WT and Clec5a−/− mice (n=5–6). * p<0.05 compared to FA mice. # p<0.05 compared to wild-type mice.

    Article Snippet: CLEC5A was assessed with α-human CLEC5A antibody (clone 283834, R&D Systems) and α-CD45 (eBioscience) using a FACSCalibur and FlowJo software.

    Techniques: Expressing